[2016 Spring Life Sciences & IBB Regular Seminar] ▶Subject: Protein Structure Prediction/Determination by Global Optimization ▶Speaker: Prof.Jooyoung Lee (Center for In Silico Protein Science and School of Computational Sciences, Korea Institute for Advanced Study) ▶Date: 4:00PM/Mar. 11(Fri.)/2016 ▶Place: Auditorium(1F), Postech Biotech Center *Abctract First, I will discuss our recent progresses on the protein structure prediction using the methodology of global optimization as illustrated in the CASP11 competition held in 2014. We will demonstrate that this method can be applied to difficult MR (molecular replacement) targets to determine X-ray crystallography structures of proteins and protein complexes, which could not be solved using conventional MR methods. We will also discuss the possible application of our method to the high throughput NMR structure determination of large proteins (over 20 kDa) and membrane proteins ▶Inquiry: Prof. Cheol-Sang Hwang (279-2352) * This seminar will be given in English. please refrain from taking photos during seminars. *