[2018 Spring Life Sciences & IBB Seminar]

▶Subject: Universal cell selective probe development platform for Human Cell Atlas

▶Speaker: Prof. Young-Tae Chang (Chemistry, POSTECH)

▶Date: 4:30PM/Mar. 2(Fri.)/2018

▶Place: Auditorium(1F), Postech Biotech Center

▶Abctract
Our body is complex systems, and discriminating them using molecular probe is challenging, but essential for specific bioimaging. The conventional method for molecular probe development relies on hypothesis driven approach, requiring a good biomarker discovery in advance. More than 10,000 synthetic organic dyes were constructed as a tool box, and numerous analytes have been tested, yielding systematic platform for sensor development for almost everything. Not only physical analytes, phantom target such as “temperature” is also pursued with biological application. Complex or unknown target problem with biological systems were also challenged, and various cell type selective probes for live bioimaging were developed. The sensors and probes developed in this study will be freely available for the chemical and biological community for common usage.
Currently, we are exploring unconventional binding targets, such as carbohydrates or lipids to expand the scope of application and the understanding of the difference among complex systems. Even more exotic target, such as cell membrane gating transporters, are also exploited for the complex system analysis from totally different aspect and mechanism.

▶Inquiry: : Prof. Seung-Woo Lee (279-2355)

* This seminar will be given in English.
Please refrain from taking photos during seminars. *