[2014 Fall Life Sciences & IBB Regular Seminar]
      
        
     ▶Subject: Chromatin Modifiers in Epigenetic Control of Cancer and Stem Cells
     
     ▶Speaker: Sung Hee Baek, Ph.D. (Department of Biological Sciences, Seoul National University)
             
     ▶Date: 4:00PM/Nov./14(Fri)/2014
            
     ▶Place: Auditorium(1F), POSTECH Biotech Center
            
             *Abctract
          Epigenetics encompass inheritable changes in gene expression profiles that occur without alterations to the genomic DNA sequence. Epigenetic modifications conduct important roles in diverse biological processes. Histones and nonhistone proteins including chromatin modifiers and transcriptional coregulators are subject to diverse epigenetic modifications including phosphorylation, acetylation, methylation, ubiquitination, and SUMOylation. These diverse post-translational modifications can modulate the activity of chromatin modifiers altering the chromatin state for either activation or repression. In this presentation, I will discuss our continued efforts to decipher epigenetic regulatory mechanism of cancer and stem cells. I will introduce newly identified signaling crosstalk regulated by chromatin modifiers and address its biological meaning in cancer and stem cells.

     ▶Inquiry: Prof. Yoontae Lee(279-2354)
           
       * This seminar will be given in English